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1

New technologies for biomarker analysis of prostate cancer progression: Laser capture microdissection and tissue proteomics

Cloud P Paweletz, Lance A Liotta, Emanuel F Petricoin III

Journal:

Year:

2001

Language:

english

File:

PDF, 256 KB

english, 2001

2

Prospective Validation of Rapid Plasma Genotyping for the Detection of EGFR and KRAS Mutations in Advanced Lung Cancer

Sacher, Adrian G., Paweletz, Cloud, Dahlberg, Suzanne E., Alden, Ryan S., O’Connell, Allison, Feeney, Nora, Mach, Stacy L., Jänne, Pasi A., Oxnard, Geoffrey R.

Journal:

Year:

2016

Language:

english

File:

PDF, 471 KB

english, 2016

3

Rapid protein display profiling of cancer progression directly from human tissue using a protein biochip

Cloud P. Paweletz, John W. Gillespie, David K. Ornstein, Nicole L. Simone, Monica R. Brown, Kristina A. Cole, Quan-Hong Wang, Jing Huang, Nan Hu, Tai-Tung Yip, William E. Rich, Elise C. Kohn, W. Marst

Journal:

Drug Development Research

Year:

2000

Language:

english

File:

PDF, 283 KB

english, 2000

4

An approach to proteomic analysis of human tumors

Michael R. Emmert-Buck, John W. Gillespie, Cloud P. Paweletz, David K. Ornstein, Venkatesha Basrur, Ettore Appella, Quan-Hong Wang, Jing Huang, Nan Hu, Phil Taylor, Emanuel F. Petricoin III

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 189 KB

english, 2000

5

Proteomic analysis of laser capture microdissected human prostate cancer and in vitro prostate cell lines

David K. Ornstein, John W. Gillespie, Cloud P. Paweletz, Paul H. Duray, Judi Herring, Cathy D. Vocke, Suzanne L. Topalian, David G. Bostwick, W. Marston Linehan, Emanuel F. Petricoin III, Michael R. E

Journal:

ELECTROPHORESIS

Year:

2000

Language:

english

File:

PDF, 364 KB

english, 2000

6

New approaches to proteomic analysis of breast cancer

Julia D. Wulfkuhle, Kelley C. McLean, Cloud P. Paweletz, Dennis C. Sgroi, Bruce J. Trock, Patricia S. Steeg, Emanuel F. Petricoin III

Journal:

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

7

Quantitative Analysis of Complex Peptide Mixtures Using FTMS and Differential Mass Spectrometry

Fanyu Meng, Matthew C. Wiener, Jeffrey R. Sachs, Chrissina Burns, Priyanka Verma, Cloud P. Paweletz, Matthew T. Mazur, Ekaterina G. Deyanova, Nathan A. Yates, Ronald C. Hendrickson

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 996 KB

english, 2007

8

Mitochondrial proteome: Altered cytochrome c oxidase subunit levels in prostate cancer

Paul C. Herrmann, John W. Gillespie, Lu Charboneau, Verena E. Bichsel, Cloud P. Paweletz, Valerie S. Calvert, Elise C. Kohn, Michael R. Emmert-Buck, Lance A. Liotta, Emanuel F. Petricoin III

Journal:

Year:

2003

Language:

english

File:

PDF, 1.04 MB

english, 2003

9

Signal pathway profiling of prostate cancer using reverse phase protein arrays

Robert L. Grubb, Valerie S. Calvert, Julia D. Wulkuhle, Cloud P. Paweletz, W. Marston Linehan, John L. Phillips, Rodrigo Chuaqui, Alfredo Valasco, John Gillespie, Michael Emmert-Buck, Lance A. Liotta,

Journal:

Year:

2003

Language:

english

File:

PDF, 104 KB

english, 2003

10

Surface enhanced laser desorption ionization spectrometry reveals biomarkers for drug treatment but not dose

Cloud P. Paweletz, Matthew C. Wiener, Jeffrey R. Sachs, Roger Meurer, Margaret S. Wu, Kenney K. Wong, Nathan A. Yates, Ronald C. Hendrickson

Journal:

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

11

Isolation and Characterization of SATB2, a Novel AT-rich DNA Binding Protein Expressed in Development- and Cell-Specific Manner in the Rat Brain

Marianna Szemes, Andrea Gyorgy, Cloud Paweletz, Albert Dobi, Denes V. Agoston

Journal:

Neurochemical Research

Year:

2006

Language:

english

File:

PDF, 592 KB

english, 2006

12

Proteomic Technologies to Study Diseases of the Lymphatic Vascular System

LEE V. LEAK, EMANUEL F. PETRICOIN III, MICHAEL JONES, CLOUD P. PAWELETZ, ALI M. ARDEKANI, VINCENT A. FUSARO, SALLY ROSS, LANCE A. LIOTTA

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 5.75 MB

2002

13

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

Nagashima, Kumiko, Krauss, Stefan, Paweletz, Cloud, Kubota, Kazuishi, Anjum, Rana, Yu, Yonghao, Kunz, Ryan C, Andersen, Jannik N, Kraus, Manfred, Keilhack, Heike

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 823 KB

english, 2009

14

Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells

Anderson, Howard A., Maylock, Caroline A., Williams, Joy A., Paweletz, Cloud P., Shu, Hongjun, Shacter, Emily

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 559 KB

english, 2002

15

Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

Paweletz, Cloud P, Charboneau, Lu, Bichsel, Verena E, Simone, Nicole L, Chen, Tina, Gillespie, John W, Emmert-Buck, Michael R, Roth, Mark J, Petricoin III, Emanuel F, Liotta, Lance A

Journal:

Year:

2001

Language:

english

File:

PDF, 577 KB

english, 2001

16

Serum proteomic signature for cystic fibrosis using an antibody microarray platform

Meera Srivastava, Ofer Eidelman, Catherine Jozwik, Cloud Paweletz, Wei Huang, Pamela L. Zeitlin, Harvey B. Pollard

Journal:

Molecular Genetics and Metabolism

Year:

2006

Language:

english

File:

PDF, 982 KB

english, 2006

17

Identification of target engagement biomarkers for MARK inhibitor discovery using quantitative mass spectrometry

Hayashi, Mansuo, Paweletz, Cloud, Yu, Shang-Shuan, Nuthall, Hugh, Northrup, Alan, Chi, An, Hendrickson, Ron

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

18

Differential mass spectrometry identifies candidate markers for Alzheimer's disease in humans

Hendrickson, Ronald C., Paweletz, Cloud, Liaw, Andy, Song, Qinghua, Lee, Anita, Li, Jenny, Meng, Fanyu, Deyanova, Ekaterina G., Mazur, Matthew, Settlage, Robert E., Wiener, Matt, Zhao, Xuemei, Seeburg

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

19

Evidence of mTOR Activation by an AKT-Independent Mechanism Provides Support for the Combined Treatment of PTEN-Deficient Prostate Tumors with mTOR and AKT Inhibitors

Zhang, Weisheng, Haines, Brian B., Efferson, Clay, Zhu, Joe, Ware, Chris, Kunii, Kaiko, Tammam, Jennifer, Angagaw, Minilik, Hinton, Marlene C., Keilhack, Heike, Paweletz, Cloud P., Zhang, Theresa, Win

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

20

Quantitative Analysis of Histone Deacetylase-1 Selective Histone Modifications by Differential Mass Spectrometry

Lee, Anita Y. H., Paweletz, Cloud P., Pollock, Roy M., Settlage, Robert E., Cruz, Jonathan C., Secrist, J. Paul, Miller, Thomas A., Stanton, Matthew G., Kral, Astrid M., Ozerova, Nicole D. S., Meng, F

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 3.72 MB

english, 2008

21

Application of an End-to-End Biomarker Discovery Platform to Identify Target Engagement Markers in Cerebrospinal Fluid by High Resolution Differential Mass Spectrometry

Paweletz, Cloud P., Wiener, Matthew C., Bondarenko, Andrey Y., Yates, Nathan A., Song, Qinghua, Liaw, Andy, Lee, Anita Y. H., Hunt, Brandon T., Henle, Ernst S., Meng, Fanyu, Funk Sleph, Holly, Holahan

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 472 KB

english, 2010

22

Monitoring cancer through the blood

Paweletz, Cloud P., Jänne, Pasi A.

Journal:

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

23

Dacomitinib as first-line treatment in patients with clinically or molecularly selected advanced non-small-cell lung cancer: a multicentre, open-label, phase 2 trial

Jänne, Pasi A, Ou, Sai-Hong I, Kim, Dong-Wan, Oxnard, Geoffrey R, Martins, Renato, Kris, Mark G, Dunphy, Frank, Nishio, Makoto, O'Connell, Joseph, Paweletz, Cloud, Taylor, Ian, Zhang, Hui, Goldberg, Z

Journal:

The Lancet Oncology

Year:

2014

Language:

english

File:

PDF, 277 KB

english, 2014

24

Laser Capture Microdissection: Beyond Functional Genomics to Proteomics

Nicole L. Simone,Cloud P. Paweletz MS,Lu Charboneau…

Journal:

Molecular Diagnosis & Therapy

Year:

2000

Language:

english

File:

PDF, 961 KB

english, 2000

25

Enhanced Ratio of Signals Enables Digital Mutation Scanning for Rare Allele Detection

Castellanos-Rizaldos, Elena, Paweletz, Cloud, Song, Chen, Oxnard, Geoffrey R., Mamon, Harvey, Jänne, Pasi A., Makrigiorgos, G. Mike

Journal:

The Journal of Molecular Diagnostics

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

26

Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M

Thress, Kenneth S, Paweletz, Cloud P, Felip, Enriqueta, Cho, Byoung Chul, Stetson, Daniel, Dougherty, Brian, Lai, Zhongwu, Markovets, Aleksandra, Vivancos, Ana, Kuang, Yanan, Ercan, Dalia, Matthews, S

Journal:

Nature Medicine

Year:

2015

Language:

english

File:

PDF, 1019 KB

english, 2015

27

In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer

Janiszewska, Michalina, Liu, Lin, Almendro, Vanessa, Kuang, Yanan, Paweletz, Cloud, Sakr, Rita A, Weigelt, Britta, Hanker, Ariella B, Chandarlapaty, Sarat, King, Tari A, Reis-Filho, Jorge S, Arteaga,

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 5.08 MB

english, 2015

28

Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer

Tolaney, Sara M., Tan, Sally, Guo, Hao, Barry, William, Van Allen, Eliezer, Wagle, Nikhil, Brock, Jane, Larrabee, Katherine, Paweletz, Cloud, Ivanova, Elena, Janne, Pasi, Overmoyer, Beth, Wright, John

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 786 KB

english, 2015

29

Genomic Analysis of Plasma Cell-Free DNA in Patients With Cancer

Oxnard, Geoffrey R., Paweletz, Cloud P., Sholl, Lynette M.

Journal:

Year:

2016

Language:

english

File:

PDF, 62 KB

english, 2016

30

Embryonic transcription factor SOX9 drives breast cancer endocrine resistance

Jeselsohn, Rinath, Cornwell, MacIntosh, Pun, Matthew, Buchwalter, Gilles, Nguyen, Mai, Bango, Clyde, Huang, Ying, Kuang, Yanan, Paweletz, Cloud, Fu, Xiaoyong, Nardone, Agostina, De Angelis, Carmine, D

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

31

CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T Cell Activation

Deng, Jiehui, Wang, Eric S., Jenkins, Russell W., Li, Shuai, Dries, Ruben, Yates, Kathleen, Chhabra, Sandeep, Huang, Wei, Liu, Hongye, Aref, Amir R., Ivanova, Elena, Paweletz, Cloud Peter, Bowden, Mic

Journal:

Cancer Discovery

Year:

2017

Language:

english

File:

PDF, 2.78 MB

english, 2017

32

Isolation and characterization of circulating melanoma cells by size filtration and fluorescent in-situ hybridization

Yanagita, Masahiko, Luke, Jason J., Hodi, Frank S., Jänne, Pasi A., Paweletz, Cloud P.

Journal:

Melanoma Research

Year:

2018

Language:

english

File:

PDF, 336 KB

english, 2018

33

False positive plasma genotyping due to clonal hematopoiesis

Hu, Yuebi, Ulrich, Bryan, Supplee, Julianna, Kuang, Yanan, Lizotte, Patrick H., Feeney, Nora, Guibert, Nicolas, Awad, Mark M., Wong, Kwok-Kin, Janne, Pasi A., Paweletz, Cloud Peter, Oxnard, Geoffrey R

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 598 KB

english, 2018

34

Liquid biopsy of fine-needle aspiration supernatant for lung cancer genotyping

Guibert, Nicolas, Tsukada, Hisashi, Hwang, David H., Chambers, Emily, Cibas, Edmund S., Bale, Tejus, Supplee, Julianna, Ulrich, Bryan, Sholl, Lynette M., Paweletz, Cloud P., Oxnard, Geoffrey R.

Journal:

Year:

2018

Language:

english

File:

PDF, 731 KB

english, 2018

35

Assessing Therapeutic Efficacy of MEK Inhibition in a KRAS G12C-Driven Mouse Model of Lung Cancer

Li, Shuai, Liu, Shengwu, Deng, Jiehui, Akbay, Esra A, Hai, Josephine, Ambrogio, Chiara, Zhang, Long, ZHOU, FANGYU, Jenkins, Russell W., Adeegbe, Dennis O, Gao, Peng, Wang, Xiaoen, Paweletz, Cloud P.,

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

36

Proteomic Patterns of Nipple Aspirate Fluids Obtained by SELDI-TOF: Potential for New Biomarkers to Aid in the Diagnosis of Breast Cancer

Paweletz, Cloud P., Trock, Bruce, Pennanen, Marie, Tsangaris, Theodore, Magnant, Collette, Liotta, Lance A., Petricoin III, Emanuel F.

Journal:

Disease Markers

Year:

2001

Language:

english

File:

PDF, 2.16 MB

english, 2001

37

Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays

Oxnard, Geoffrey R., Paweletz, Cloud P.

Journal:

Year:

2018

Language:

english

File:

PDF, 39 KB

english, 2018

38

Unraveling the clinicopathological features driving the emergence of ESR1 mutations in metastatic breast cancer

Kuang, Yanan, Siddiqui, Bilal, Hu, Jiani, Pun, Matthew, Cornwell, MacIntosh, Buchwalter, Gilles, Hughes, Melissa E., Wagle, Nikhil, Kirschmeier, Paul, Jänne, Pasi A., Paweletz, Cloud P., Lin, Nancy U.

Journal:

npj Breast Cancer

Year:

2018

Language:

english

File:

PDF, 987 KB

english, 2018

39

Cell-Free DNA in Oncology: Gearing up for Clinic

Ulrich, Bryan C., Paweletz, Cloud P.

Journal:

Annals of Laboratory Medicine

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

40

Denaturation-Enhanced Droplet Digital PCR for Liquid Biopsies

Fitarelli-Kiehl, Mariana, Yu, Fangyan, Ashtaputre, Ravina, Leong, Ka Wai, Ladas, Ioannis, Supplee, Julianna, Paweletz, Cloud, Mitra, Devarati, Schoenfeld, Jonathan D., Parangi, Sareh, Makrigiorgos, G.

Journal:

Clinical Chemistry

Year:

2018

Language:

english

File:

PDF, 2.26 MB

english, 2018

41

Salivary HPV DNA informs locoregional disease status in advanced HPV-associated oropharyngeal cancer

Hanna, Glenn J., Lau, Christie J., Mahmood, Umair, Supplee, Julianna G., Mogili, Abhishek R., Haddad, Robert I., Jänne, Pasi A., Paweletz, Cloud P.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.04 MB

english, 2019

42

Sensitivity of next-generation sequencing assays detecting oncogenic fusions in plasma cell-free DNA

Supplee, Julianna G., Milan, Marina S.D., Lim, Lee P., Potts, Kristy T., Sholl, Lynette M., Oxnard, Geoffrey R., Paweletz, Cloud P.

Journal:

Year:

2019

File:

PDF, 660 KB

2019

43

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

Rashidian, Mohammad, LaFleur, Martin W., Verschoor, Vincent L., Dongre, Anushka, Zhang, Yun, Nguyen, Thao H., Kolifrath, Stephen, Aref, Amir R., Lau, Christie J., Paweletz, Cloud P., Bu, Xia, Freeman,

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

Language:

english

File:

PDF, 2.43 MB

english, 2019

44

Effect of Erlotinib Plus Bevacizumab vs Erlotinib Alone on Progression-Free Survival in Patients With Advanced EGFR -Mutant Non–Small Cell Lung Cancer

Stinchcombe, Thomas E., Jänne, Pasi A., Wang, Xiaofei, Bertino, Erin M., Weiss, Jared, Bazhenova, Lyudmila, Gu, Lin, Lau, Christie, Paweletz, Cloud, Jaslowski, Anthony, Gerstner, Gregory J., Baggstrom

Journal:

Year:

2019

Language:

english

File:

PDF, 312 KB

english, 2019

45

EGFR-Mutated Lung Cancers Resistant to Osimertinib through EGFR C797S Respond to First-Generation Reversible EGFR Inhibitors but Eventually Acquire EGFR T790M/C797S in Preclinical Models and Clinical Samples

Rangachari, Deepa, To, Ciric, Shpilsky, Jason E., VanderLaan, Paul A., Kobayashi, Susumu S., Mushajiang, Mierzhati, Lau, Christie J., Paweletz, Cloud P., Oxnard, Geoffrey R., Jänne, Pasi A., Costa, Da

Journal:

Journal of Thoracic Oncology

Year:

2019

Language:

english

File:

PDF, 1.39 MB

english, 2019

46

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

Ge, Jennifer Y., Shu, Shaokun, Kwon, Mijung, JovanoviÄ, Bojana, Murphy, Katherine, Gulvady, Anushree, Fassl, Anne, Trinh, Anne, Kuang, Yanan, Heavey, Grace A., Luoma, Adrienne, Paweletz, Cloud, Thorn

Journal:

Nature Communications

Year:

2020

File:

PDF, 6.22 MB

2020

47

Traditional Diagnostics versus Disruptive Technology: The role of the pathologist in the era of liquid biopsy

Sholl, Lynette M., Oxnard, Geoffrey R., Paweletz, Cloud P.

Journal:

Cancer Research

Year:

2020

File:

PDF, 688 KB

2020

48

Plasma IL-6 changes correlate to PD-1 inhibitor responses in NSCLC

Keegan, Alissa, Ricciuti, Biagio, Garden, Padric, Cohen, Limor, Nishihara, Reiko, Adeni, Anika, Paweletz, Cloud, Supplee, Julianna, JÃ¤nne, Pasi A, Severgnini, Mariano, Awad, Mark M, Walt, David R

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2020

File:

PDF, 4.96 MB

2020

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